Day: May 4, 2020

Common ingredient in cough medicine may help coronavirus grow, study finds

Common ingredient in cough medicine may help coronavirus grow, study finds

A “blueprint” that reveals how the new coronavirus infects human cells and which drugs could impact that process has also led researchers to caution about a common ingredient in cough medicine.

Dextromethorphan — an over-the-counter cough suppressant found in more than 120 cough and cold products — was found to have “pro-viral activity” in lab experiments and “therefore its use should merit caution and further study in the context of COVID-19,” wrote the authors of the study, published in Nature on Thursday.

Since coughing is a key warning sign of the coronavirus infection, that would be extra worrisome for the many people trying to soothe their symptoms with cough syrup or lozenges.

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But the findings don’t necessarily mean people should stop using medicine with this ingredient, said Brian Shoichet, one of the researchers and professor of pharmaceutical chemistry

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Take A (Virtual) Tour Of The NPG's Hockney Exhibition

Take A (Virtual) Tour Of The NPG’s Hockney Exhibition

The galleries are shut, the museums are closed. But worry not, art fans. We’ve tapped some of the art world’s leading curators, collectors and experts to talk us through the exhibitions none of us can attend in person. Here Nicholas Cullinan, director at the National Portrait Gallery, talk us through his highlights from its blockbuster show, David Hockney: Drawing From Life.


My Parents and Myself (1976)

david hockney"my parents and myself"
David Hockney,

Richard Schmidt

David Hockney was born in Bradford, West Yorkshire. His father worked as a clerk, but was an amateur artist and anti-smoking campaigner (which is somewhat ironic, given his son’s later, very vocal position on this issue), who was well-known for his strong political views. Laura Hockney was a quieter but strong matriarchal figure, a vegetarian and committed Methodist.

Hockney was visited by his parents whilst he was living intermittently in Paris (1973-5). It was there that he made the preparatory

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Critical 48 hours in virus fight

Critical 48 hours in virus fight

If you want to receive twice-daily briefings like this by email, sign up to the Front Page newsletter here. For two-minute audio updates, try The Briefing – on podcasts, smart speakers and WhatsApp.

Cabinet set to sign off blueprint to vary lockdown

The next 48 hours are key. Boris Johnson’s arrival back in Downing Street kick-started a crucial week in the coronavirus crisis that will do so much to set the tone of his premiership over the next few years. The Prime Minister returned with a pledge to “refine the economic and social restrictions” that have kept millions of people at home and mothballed the British economy. His Government is already committed to reviewing the lockdown by Thursday next week. But all eyes are now on an earlier meeting of Mr Johnson’s full Cabinet this Thursday – which is expected to sign off a blueprint to vary the rules. Chief

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How much do retirement homes cost?

Edited Transcript of VRTX earnings conference call or presentation 29-Apr-20 9:00pm GMT

Cambridge May 1, 2020 (Thomson StreetEvents) — Edited Transcript of Vertex Pharmaceuticals Inc earnings conference call or presentation Wednesday, April 29, 2020 at 9:00:00pm GMT

* Charles F. Wagner

* Stuart A. Arbuckle

Stifel, Nicolaus & Company, Incorporated, Research Division – Co-Head of the Biotech Team, MD & Senior Analyst

* Philip M. Nadeau

Good evening. Welcome to the Vertex First Quarter 2020 Financial Results Conference Call. This is Michael Partridge, Senior Vice President of Investor Relations for Vertex. Making prepared remarks on the call tonight, we have Dr. Reshma Kewalramani, Vertex’s CEO and President; Stuart Arbuckle, Chief Commercial Officer; and Charlie Wagner, Chief Financial Officer. We recommend that you access the webcast slides on our website as you listen to this call. This conference call is being recorded, and a replay will be available on our website.

We will make forward-looking statements on this call that are subject to … Read More

India faces spike in coronavirus cases, says study, in test for health system

Global Platform Shares How Coronavirus Affects Pediatric Cancer Treatment

A group of 24 clinicians from 14 countries gathered at the beginning of March for an annual St. Jude Global course on infection care and prevention, adjusting their final two days to focus on the novel coronavirus, which had been bubbling up since December.

As they shared best practices and examined the latest information on the virus’ impact on their young patients, an idea formed to provide a platform that would educate and connect health care providers around the world to share how the COVID-19 disease affects the treatment of children with cancer.

Thus, the Global COVID-19 Observatory and Resource Center for Childhood Cancer was created as a global pediatric cancer and COVID-19 registry, resource and collaboration space. So far, close to 300 providers from multiple countries, including Italy, Spain and China, have connected to the platform since its launch mid-April, Dr. Carlos Rodriguez-Galindo, director of St. Jude Global, tells

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Why it's risky to promise a coronavirus vaccine and cure

Why it’s risky to promise a coronavirus vaccine and cure

Rubber stoppers are placed on filled vials of the drug remdesivir at a Gilead Sciences manufacturing plant. <span class="copyright">(Associated Press)</span>
Rubber stoppers are placed on filled vials of the drug remdesivir at a Gilead Sciences manufacturing plant. (Associated Press)

A surge of optimism has followed each recent announcement about possible cures and vaccines for COVID-19, including this week’s disclosure of a treatment that was first developed for the Ebola virus.

But there is a price to pay for promising too much as the economy reels and the world anxiously awaits even a marginally effective therapeutic. Some promising announcements have been followed by reality checks, further muddling the picture about which ones will come to the rescue.

The latest came this week after Dr. Anthony Fauci, the chief of the federal government’s top institute for infectious diseases, indicated that an anti-viral drug developed by Bay Area biotech giant Gilead Sciences sped up by several days the recovery of about half the people with COVID-19.

That same day, however, the celebration was

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What If This Virus Can Teach Us to Change Ourselves?

What If This Virus Can Teach Us to Change Ourselves?

In 1866 the United States of America was connected to the rest of the world by an underwater cable that stretched from the wilds of Canada to the wilds of Ireland. Two ships met mid-Atlantic and then unspooled a cable that went from the town of Heart’s Content in Newfoundland all the way to Valentia Island in Kerry.

The cable was thousands of miles long and went three miles deep in places. Seven strands of copper lay at its core.

The first public message that pulsed transatlantically was a telegraph that went between President Buchanan and Queen Victoria. The New World and the Old World had been joined. It was considered one of the great undertakings of the 19th century, at the time near enough to the equivalent of putting a man on the moon. Nothing would be the same again: not the stock market, not business, not politics, not

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Experts warn that hospitals lack enough intensive care nurses to restart operations

Experts warn that hospitals lack enough intensive care nurses to restart operations

The NHS lacks enough essential critical-care nurses for hospitals to restart some services while thousands of Covid-19 patients remain in hospital, experts have warned.

The head of NHS England, Sir Simon Stevens, wrote to hospitals earlier this week asking NHS trusts to begin non-coronavirus-related activity again now that the health service had come through the worst of the Covid-19 surge.

However, the Faculty of Intensive Care Medicine (FICM) and the British Association of Critical Care Nurses (BACCN) warned in a joint statement that there are not enough staff to safely cope with additional work.

The two organisations said any activity that was frozen ahead of the coronavirus outbreak should not be restarted until the ratio of patients to nurses fell to 2 to 1.

Nicki Credland, chair of the BACCN, said: “We currently remain in full surge (with an average ratio of six patients to every one intensive care qualified

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A Week Living In A Converted Van On A $12,000 Salary

A Week Living In A Converted Van On A $12,000 Salary

Welcome to Money Diaries, where we’re tackling what might be the last taboo facing modern working women: money. We’re asking women how they spend their hard-earned money during a seven-day period — and we’re tracking every last dollar.

Today: a writer who makes $12,000 a year and spends some of her money this week on dinosaur stamps.

Editor’s Note: This is a follow-up diary for the Money Diary entitled “A Week As A Nomad On $12,000 A Year” You’ll want to read that first, here. 

Occupation: Writer
Industry: Publishing
Age: 38
Location: Nomadic
Salary: $12,000
Net Worth: $20,000 in a Roth IRA before COVID-19 it but I haven’t looked since the market plummeted.
Debt: I’ve got about $2,000 on a credit card that I’ll pay off before the payment is due.
Pronouns: She/her

Monthly Expenses
Rent: $0 (I own and live in a van and only have to pay … Read More

The Incredible Joy of Watching a Patient Recover From COVID-19

The Incredible Joy of Watching a Patient Recover From COVID-19

This story is part of our Self-Care Is Essential project exploring the simple power of caring for yourself in times of crisis

Nava Greenfield, a board-certified dermatologist with Schweiger Dermatology Group, is caring for coronavirus patients at New York City’s Mount Sinai Hospital. Here, she tells Allure, in her own words, why she was inspired to volunteer, what it’s like on the front lines of COVID-19, and how New York City hospitals are coping.

I’m a dermatologist and one of the regional medical directors for the Schweiger Dermatology Group. At the beginning of March, we were following the situation with the novel coronavirus closely and having conversations about what we were going to do as a practice. It was really unclear how it was going to unfold, and then it happened really, really rapidly. The middle of March is when we decided to close our offices for all nonurgent issues

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